Engineered with bio-identical 100% human-homologous Recombinant Type III Collagen, this anti-aging serum delivers cellular-level matrix reconstruction to smooth facial wrinkles and restore dermal elasticity. Featuring a unique self-assembling triple-helix structure with a precise 164.88° flexible curvature angle, it integrates seamlessly with human dermal fibroblasts. Synergized with Acetyl Hexapeptide-8 ("topical botox") and multi-depth collagen peptides, it offers prestige brands a medical-grade OEM/ODM solution for targeted wrinkle relaxation and firming.
Our proprietary formula operates through a dual biological mechanism: restoring extracellular matrix (ECM) architecture while relaxing expression-induced dynamic wrinkles:
100% Homologous Triple-Helix Assembly: Features a bio-engineered 164.88° flexible bending angle identical to natural human Type III collagen. Confirmed by Cryo-ET electron tomography, it spontaneously self-assembles into nano-fibrils that penetrate transdermally to guide cell migration and collagen proliferation.
Botulinum-Like Neuromuscular Blockade: Acetyl Hexapeptide-8 competes with SNAP-25 protein in the SNARE complex, suppressing acetylcholine release at neuromuscular synapses to safely relax facial expression lines without invasive injections.
| Key Ingredient | Primary Function & Mechanism |
|---|---|
| Recombinant Type III Humanized Collagen | 100% bio-identical sequence; rebuilds ECM scaffolds, reactivates dormant fibroblasts, and promotes structural dermal repair. |
| Acetyl Hexapeptide-8 (Argireline) | Inhibits neurotransmitter release to relax expression muscles, visibly flattening forehead lines and crow's feet. |
| Hydrolyzed & Soluble Collagen Complex | Diffuses deep into dermal layers, inhibits tyrosinase activity to prevent pigmentation, and reinforces moisture retention. |
| Oligopeptide-1 (EGF Mimic) | Enhances cell proliferation and metabolic turnover while repairing damaged collagen and elastin fiber networks. |
| Tremella Fuciformis & Hyaluronic Acid | Forms a protective hydro-gel matrix thatlocks in deep hydration and reduces surface friction for velvety smooth skin texture. |
INCI Highlights: Zero non-human amino acid sequences. Mass spectrometry verified 100% human-homologous purity. Sterilization-grade formulation free from parabens, mineral oils, and artificial colorants.
35% Dynamic Wrinkle Reduction: Clinical trials evaluated by Intertek (using VISIA-CR and Primos instrumentation) demonstrate up to a 35% reduction in wrinkle count and depth over 4 weeks.
Eye Contour & Forehead Smoothing: Significantly decreases wrinkle area and wrinkle length around the outer eye corners (crow's feet) and forehead regions.
Skin Elasticity & Barrier Restoration: Elevates Cutometer elasticity parameters (Q1/R2) while suppressing IL-6 inflammatory factors, achieving zero skin irritation in 30-subject human patch tests.
Manufactured under ISO 22716 and GMPC cleanroom standards. Verified by mass spectrometry sequencing for 100% human homology and validated by Intertek third-party clinical efficacy and human patch safety testing.
We empower global luxury skincare brands with patent-backed, bio-engineered recombinant collagen formulations. View our full certifications here.
High-Tech Recombinant Platform: Medical-grade Type III humanized collagen featuring authentic 164.88° triple-helix self-assembly technology.
Certified Cleanroom Manufacturing: Operating under ISO 22716 and GMPC guidelines with FDA registration for global market compliance.
Complete OEM/ODM Turnkey Solution: Custom glass dropper packaging, concentration adjustments, and full regulatory dossiers (MSDS, COA, Intertek test reports).
What makes Recombinant Human Type III Collagen superior to animal-derived collagen?
Animal collagen (derived from pig or bovine) carries risk of viral pathogens, immunogenicity, and poor skin absorption due to non-human amino acid structures. Recombinant Humanized Collagen is 100% bio-identical to human skin collagen, offering zero rejection risk, high transdermal absorption, and superior cell-adhesion activity.
How quickly can users see results on expression wrinkles with this serum?
Thanks to the synergy of Acetyl Hexapeptide-8 and self-assembling collagen nano-fibrils, clinical testing shows visible skin elasticity improvement within 14 days, with maximum 35% wrinkle reduction achieved after 28 days of twice-daily use.
Intimate Gel Tech & Mucosal Repair
Intimate Gel Tech & Mucosal Repair
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